Modification

• Synthesis

Synthesis

Modification List

Modification	DNA Synthesis		RNA Synthesis		Notes
	Reverse-phase cartridge purification	HPLC purification	Reverse-phase cartridge purification	HPLC purification
5′ Amination (C6)	A	A	A	A	Structural formula
3′ Amination (C6)	A	A	A	A	Structural formula
5′-EC Amino Linker	A	A	A	A	Structural formula
Amino(C6)-dT insertion	A	A	A	A	Structural formula
5′ Biotin	A	A	A	A	Structural formula
3′ Biotin	A	A	A	A	Structural formula
5’Biotin(TEG)	A	A	A	A	Structural formula
5′ Cyanine3	N/A	A	N/A	A	Structural formula
5′ Cyanine5	N/A	A	N/A	A	Structural formula
3’Cyanine3	N/A	A	N/A	A	Structural formula
3’Cyanine5	N/A	A	N/A	A	Structural formula
5′ Phosphorylation	A	A	N/A	A	Structural formula
3′ Phosphorylation	A	A	A	A	Structural formula
5′ FITC (6-FAM)	N/A	A	N/A	A	Structural formula
3′ FITC (6-FAM)	A	A	A	A	Structural formula
Fluorescein-dT insertion	A	A	A	A	Structural formula
5′ TAMRA	N/A	A	N/A	A	Structural formula
3′ TAMRA	N/A	A	N/A	A	Structural formula
5′ Rhodamine (ROX)	N/A	A	N/A	A	Structural formula
3′ Rhodamine (ROX)	N/A	A	N/A	A	Structural formula
3′ BHQ1	N/A	A	N/A	A	Structural formula
3′ BHQ2	N/A	A	N/A	A	Structural formula
3′ BHQ3	N/A	A	N/A	A	Structural formula
Real time PCR probe	N/A	A	N/A	N/A	Structural formula
5′ Cholesterol	N/A	A	N/A	A	Structural formula
3′ Cholesterol	N/A	A	N/A	A	Structural formula
3′ idT	A	A	A	A	Structural formula
5′ Thiol (C6)	N/A	A	N/A	A	Structural formula
3′ Thiol (C3)	N/A	A	N/A	A	Structural formula
5′ Azide	N/A	A	N/A	A	Structural formula
3′ Azide	N/A	A	N/A	A	Structural formula
5′ Alkynyl	N/A	A	N/A	A	Structural formula
3′ Alkynyl	N/A	A	N/A	A	Structural formula
5’DBCO(TEG)	N/A	A	N/A	A	Structural formula
3′-(2′,3′-ddC)	A	A	A	A	Structural formula
3’Dabcyl	N/A	A	N/A	A	Structural formula
Spacer C3	A	A	A	A	Structural formula
Spacer C12	A	A	A	A	Structural formula
Spacer 9	A	A	A	A	Structural formula
Spacer 18	A	A	A	A	Structural formula
Uracil insertion	A	A	A	A	Structural formula
Inosine insertion	A	A	A	A	Structural formula
Phosphorothioated	A	A	A	A	Structural formula
d-Spacer	A	A	A	A	Structural formula
r-Spacer	A	A	A	A	Structural formula
RNA-T (ribothymidine) insertion	A	A	A	A	Structural formula
Methylene Bicyclo Nucleic acid	A	A	A	A	Structural formula
Artificial acyclic nucleic acid (SNA)	N/A	A	N/A	A	Structural formula
Artificial acyclic nucleic acid (iL-aTNA)	N/A	A	N/A	A	Structural formula
2′-O-Methylated RNA insertion	A	A	A	A	Structural formula
2′-Fluoro RNA insertion	A	A	A	A	Structural formula
2′-O-MOE insertion	A	A	A	A	Structural formula
5-Methyl-dC insertion	A	A	A	A	Structural formula
8-Bromo-dA insertion	A	A	A	A	Structural formula
5-Bromo-dU insertion	A	A	A	A	Structural formula
pseudo-dU insertion	A	A	A	A	Structural formula
pseudo-rU insertion	A	A	A	A	Structural formula
N6-Me-dA	A	A	A	A	Structural formula
8-oxo-dG	N/A	A	N/A	A	Structural formula
8-oxo-dA	N/A	A	N/A	A	Structural formula
8-Amino-dA	A	A	A	A	Structural formula
Inosine (RNA)	A	A	A	A	Structural formula
2-Amino-A (= 2,6-diaminopurine) (RNA)	N/A	A	N/A	A	Structural formula
Photocrosslinkable oligo CNV series (CNV-K)	A	A	A	A	Structural formula
Photocrosslinkable oligo CNV series (CNV-D)	A	A	A	A	Structural formula

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