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Product Options
Various options are available depending on your application and experimental requirements.
Please note that some options may require additional lead time beyond the standard turnaround time.
in vivo grade
Na+ Salt Exchange
By replacing the counter cation from TEA+ to Na+, toxicity in in vivo experiments can be avoided.
| Item | Synthesis Scale | Price (JPY) |
| Na+ Salt Exchange* | 1 μmol | 12,000 |
| 0.5 mg | 14,000 | |
| 1 – 19 mg | 15,000 | |
| 20 – 199 mg | 40,000 | |
| 200 – 1000 mg | 60,000 |
- For amounts over 1 g, the charge will be 60,000 JPY × number of grams.
Endotoxin Testing
To ensure that our products can be used without concern for in vivo toxicity, we confirm that the endotoxin level is below the guaranteed value.
| Item | Price (JPY) |
| Endotoxin Testing* | 30,000 |
- Guaranteed level: ≤ 5 EU/mg. For modified oligonucleotide products, please contact us separately.
Delivery Form
You can add the following options for immediate use in experiments.
| Item | Price (JPY) |
| Annealing | Free |
| Supplied in solution*1 | Free |
| Aliquoting*2 | Free (up to 10 aliquots) |
- This option is available for DNA products (including modified DNA).
- For 11 or more aliquots, please contact us.
Quality Control
You can choose from the following QC options based on your experiment.
| Item | Price (JPY) |
| Reverse-phase HPLC analysis | 20,000 |
| Ion-exchange HPLC analysis (up to 30 mer) | 25,000 |
DNA Synthesis Options
Your regular primers can be made RNase-free – ideal for RNA experiments such as reverse transcription (RT-PCR).
| Item | Price (JPY) |
| RNase-free product (without QC) | 2,000 |
| RNase-free product (with QC)* | 20,000 |
- For products with QC, RNase activity is verified to be absent by measuring degradation profiles using a Bioanalyzer or TapeStation.
Mixed Bases
Suitable for degenerate PCR, SELEX (aptamer screening), and similar applications.
Custom ratio adjustment is available; pricing is per adjusted base mix.
| Item | Price (JPY) |
| Standard mix (DNA)* | Free |
| Custom ratio adjustment (DNA) | 2,000 |
| Custom ratio adjustment (RNA) | 5,000 |
| Custom mixed bases (DNA, RNA, Modified Base) | Please contact us |
- Same as our standard “Mixed Bases (DNA)”. Mixing is free; base unit price is identical to DNA.
| e.g. | DNA custom base mixture 1 (dG:dC = 5:3) |
| DNA custom base mixture 2 (dA:dG:dC:dT = 2:1:3:1) | |
| RNA custom base mixture 3 (rG:rC:rU = 1:4:7) | |
| When synthesizing using the three adjusted mixtures above, the total charge will be: Oligo synthesis fee + (2,000 × 2 mixtures) + (5,000 × 1 mixture) |