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Custom DNA Synthesis
Custom DNA Price List #1

Unit : Japanese Yen (tax exclusive)          
Service Description Synthesis Scale Notes
OLIGO
KIDS
25nmol 0.05Ámol 0.2Ámol 1Ámol
Number of Base *1 11 -
30mers
11 -
30mers
11 -
50mers
- 99mers - 120mers 121 -
200mers
Price of Oligo Synthesis
Normal synthesis price 80 120 140 240 300 350 per base
Degenerated base price*2 - - 140 240 300 - per base /more than 0.05Ámol scale
Inosine insertion - - 1,500 1,500 2,500 - per base /more than 0.05Ámol scale
Uracil insertion - - - 5000/
/ 5 sites
10,000
/ 5 sites
-
Phosphorothioate - - - - 200
/site
-
RNA-T (ribothymidine) insertion - - - 12,000
/site
18,000
/site
-
2'-O-Methylated RNA (A, C, G, U) insertion - - - 1,000
/site
2,000
/site
-
2'-O-Methylated RNA (T) insertion - - - 12,000
/site
18,000
/site
- Flat fare for 3 sites per 1 oligo
2'-Fluoro-RNA (C,U) insertion - - - 1,200
/site
2,300
/site
-
2'-Fluoro-RNA (A,G) insertion - - - 1,500
/site
3,000
/site
-
5-Methyl-dC - - - 12,000 24,000 - Flat fare for 5 sites per 1 oligo
8-Bromo-dA - - - 12,000 18,000 -
5-Bromo-dU - - - 7,000 11,000 -
N6-Me-dA - - - 19,000 28,500 -
8-oxo-dG - - - 20,000 30,000 -
8-oxo-dA - - - 16,000 24,000 -
8-Amino-dA - - - 20,000 30,000 -
Inosine (RNA) - - - 10,000 15,000 -
2-Amino-A (= 2,6-diaminopurine) (RNA) - - - 23,000 34,500 -
Purification *3 (per tube)
Gel Filtration No charge No charge No charge No charge No charge - 11 - 50mers
Reverse-phase Cartridge Purification 2,000 2,000 2,000 2,000 4,000 - Up to 70mers
Reverse-phase Cartridge Purification
(with MS data)*4
- 3,500 3,500 3,500 6,000 - Up to 50mers
HPLC Purification - 6,000 6,000 6,000 12,000 - Up to 120mers
IEX HPLC Purification - - - 12,000 - - Between 11 and 30 mers
(Degenerated base not available)
High Purification (20 -30 mers)*5 - - - - 28,000 - Between 20 and 30 mers
(Degenerated base not available)
High Purification (31 -50 mers)*5 - - - - 30,000 - Between 31 and 50 mers
(Degenerated base not available)
PAGE Purification - - - 7,000 14,000 14,000 11 - 200mers
Modification (per tube)
(3' end modification is only available for the length between 11 and 50mers.)
5' Amination (C6) - - - 5,000 9,000 - Number in brackets means the
numberof carbon chain linkers.
3' Amination (C6) - - - 5,000 11,000 - Number in brackets means the
numberof carbon chain linkers.
5'-EC Amino Linker - - - 5,000 9,000 -
5' Biotin - - - 9,000 17,000 -
3' Biotin - - - 8,000 14,000 -
5' Cyanine3 - - - 16,000 24,000 -
5' Cyanine5 - - - 16,000 24,000 -
5' Phosphorylation - - - 8,000 11,000 -
3' Phosphorylation - - - 8,000 14,000 -
5' FITC (6-FAM) - - - 9,000 19,000 -
3' FITC (6-FAM) - - - 10,000 20,000 -
5' TAMRA - - - 10,000 29,000 -
3' TAMRA - - - 9,500 29,000 -
5' Rhodamine (ROX) - - - 10,000 30,000 -
3' Rhodamine (ROX) - - - 10,000 29,000 -
3' BHQ1 - - - 17,000 26,000 -
3' BHQ2 - - - 17,000 26,000 -
Real Time PCR Probe (15-30mers) - - - 27,000 - - including synthesis and purification
fee (delivery in dried form)
5' Cholesterol - - - 17,000 26,000 -
3' Cholesterol - - - 12,000 18,000 -
3' idT - - - 4,500 9,000 -
5' Thiol*6 (C6) - - - 12,000 19,000 - Number in brackets means the number
of carbon chain linkers.
3' Thiol*6 (C3) - - - 12,000 20,000 - Number in brackets means the number
of carbon chain linkers.
5' Azide - - - 12,000 20,000 -
3' Azide - - - 12,000 22,000 -
5' Alkynyl - - - 12,000 20,000 -
3' Alkynyl - - - 12,000 22,000 -
d-Spacer - - - 9,000/site 14,000/site -
r-Spacer - - - 13,000/site 19,500/site -
Spacer C3 - - - 8,000 12,000 -
Spacer C12 - - - 10,000 15,000 -
Spacer 9 - - - 8,000 12,000 -
Spacer 18 - - - 10,000 15,000 -
Delivery state *7 (dried)
* Real Time PCR Probe is a probe with modification of 5'FITC(6-FAM) 3'TAMRA.
* Please calculate the total fee as follows: (synthesis fee) X (number of bases) + (purification fee)
   + (modification fee)


Custom DNA Price List #2
Large Amount Synthesis
* For the orders more than 100mg, "Large Scale Synthesis" is recommended. Click here for the details.
Unit : Japanese Yen (tax exclusive)
Yield Guarantee Synthesis Price HPLC Purification Phosphorothioate Oligo*8 5' FITC 5' Biotin 5' Amination 5' Phosphorylation
per base per tube per position per tube per tube per tube per tube
1mg 580 20,000 500 27,000 31,000 15,000 28,000
2mg 720 24,000 600 35,000 45,000 21,000 44,000
3mg 860 28,000 700 47,000 61,000 28,000 58,000
4mg 1,000 32,000 800 62,000 81,000 37,000 72,000
5mg 1,140 36,000 900 77,000 101,000 46,000 85,000
Order Acceptance and Shipment
Order Acceptance week E-mail WEB
Mon. through Fri. 17:00 19:00(*1)
*1 Orders accepted before 19:00 are to be shipped on the next business day
for 11~40 mers oligos with Gel Filtration or Reverse-phase Cartridge
Purification. For the other DNA/RNA synthesis, orders are accepted untill 18:00.
Sat. 16:30
Sun. & Holidays 12:00
Shipment Mon. through Sat. Shipment is made.
Sun. & Holidays No shipment is made.
Delivery Mon. through Fri. Pl. inquire to HSS head office.
Notice
*1 The fee for 10mers will be charged when the order is under 10mers.
*2 Degenerated base is available for more than 0.05µmol scale.
*3 Each purification grade has applicable number of bases.
Basically, product longer than 71 mers is available with HPLC and PAGE purification only.
Please note that gel filtration for the product shorter than 10 mers is not available.
*4 The molecular weight data of LC-MS will be enclosed to the product under 50mers.
*5 Combination of HPLC + IEX HPLC purifications are applied for oligos of 20 -30 mers, and HPLC + PAGE purifications for oligos of 31 -50 mers.
*6 Products with Thiol modification have the protecting group on to avoid disulfide linkage. The protocol for deblocking will be enclosed with the shipment of the product.
*7 Products will be dried for delivery with some exceptions. Please inquire for delivery in other state.
*8 Molecular weight will be measured by LC-MS to ensure Phosphorothioate oligo is correctly produced before shipment.
LC-MS measurement is available limited to oligo under 50mers.
Phosphorothioate oligo fee is calculated as follows: (the price of Phosphorothioate oligo per position) X (number of positions)
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